Quicksilver Scientific LipoCalm is a breakthrough in nutritional sleep support. If you find yourself struggling to de-stress and wind-down before bed, then this is the supplement for you. Features a proprietary liposomal blend of PharmaGABA and a number of potent botanical extracts which have displayed the potential to activate GABA receptors in the brain. Quicksilver Delivery Systems™ might aid in transporting nutritional compounds past the blood-brain barrier.
GABA – Of all the neurotransmitters in the human brain, none are more closely tied to sleep than GABA receptors. As one landmark review on the subject states “It is well established that activation of GABA(A) receptors favors sleep.”1 Many of the most popular hypnotic medications are designed to do exactly this.
Skullcap has benefits for natural sleep and is used in Quicksilver Scientific LipoCalm to support GABA
Skullcap, or Scutellaria
While the idea of consuming neurotransmitters might sound strange to some, GABA actually occurs naturally in certain foods, such as the popular fermented Korean dish known as kimchi. Quicksilver Scientific LipoCalm uses PharmaGABA because it is the highest quality natural GABA extract derived from the same lactic acid bacteria used in the making of kimchi. Supplements using low-cost synthetic GABA extracts are unlikely to cross the blood-brain barrier and have any tangible effect on access to relaxation and sleep.
Skullcap – Also known by its scientific name of scutellaria lateriflora, skullcap root extract is one of the most relevant natural extracts in scientific research surrounding sleep and relaxation. One study found that it was capable of improving sleep behavior in vertebrae models by way of GABA(A)-BZD receptor binding.2 Another study found skullcap, in combination with romaine lettuce extract, induced significantly enhanced global mood without a reduction in energy or cognition in healthy volunteers.3
Passionflower – Similar to other ingredients in LipoCalm, passionflower has been shown to effect GABA(A) receptors. In addition, clinical trials have revealed that this herb may have a particularly strong effect on feelings of stress and anxiety.4,5
Chamomile – Perhaps the most popular of all herbal sleep support agents. For hundreds of years chamomile tea has been recommended as a pre-bedtime drink to aid in sleep and relaxation. Some people mistakenly assume that this is only because chamomile tea is free from caffeine unlike most teas commonly found around the house. This is not the case. One study reported chamomile exhibiting benzodiazepine-like hypnotic activity in sleep-disturbed rats.6 Another study has reported a significant presence of benzodiazepine-like compounds in chamomile extracts which may be capable of effecting GABA receptors in the brain.7