An impressive amount of research and long history of clinical use documents the benefits of SAMe. As a modulator of cell membrane fluidity and neurochemical activity in the central nervous system, it helps support mood and optimal brain function.† The sulfur in SAMe is used to help build cartilage and strong joints and for synthesis of taurine and glutathione, used in liver detoxification processes.† SAMe also helps synthesize polyamines required for normal cell growth.† The reactive nature of SAMe prevents it from being used in combination nutrient products, but it can be stabilized as a single ingredient with careful manufacturing and an enteric tablet coating. This product provides a pharmaceutical grade, stabilized SAMe manufactured under low temperature and low humidity conditions. An enteric tablet coating is applied to further ensure a biologically active product. Each tablet contains a full 200 mg of elemental SAMe from 400 mg SAMe tosylate disulfate.